I was able to finish the Broad Street Run 5 minutes and 2 seconds faster than I did last year. I took 247th place. I think it is due to two reasons:

1) I have been taking micronized resveratrol through the buccal muscosa, and
2) I went through a divorce

The resveratrol may increase my endurance. I was taking resveratrol last year, but I was swallowing a capsule that was not micronized. The resveratrol I take now, and the way that I take it, should increase the bioavailability of it.
I have also been running regularly since getting divorced, to blow off steam and stay healthy.

Thanks to pythagoruz for the video link. I have been taking micronized resveratrol through the buccal mucosa on a daily basis for the last few months and feel great.

Zombies Meet Resveratrol!!! – The most amazing bloopers are here

So I’ve started taking micronized resveratrol through the cheek. I read that “the most efficient way of administering resveratrol in humans appears to be buccal delivery, that is without swallowing, by direct absorption through the inside of the mouth.” You can read more about it on wikipedia.
Oral bioavailability of resveratrol is low because it is rapidly metabolized in the intestines and liver, so hopefully this will help me to get more into my blood stream and to keep it there longer.

Tomorrow I will double my intake of resveratrol from 250mg to 500mg. If that goes well, then I will most likely bump it up to 750mg after a few weeks. Why? Because even though it is an experimental supplement with potentially dangerous side-effects, I have been taking it for about a year and I think my health has only improved because of it. For example, I ran the fastest pace I’ve run before – without training. Also, I’d like to start taking the Transmax along with the one capsule of Bioforte that I am currently taking daily.
This will be pretty extreme resveratrol consumption – the equivalent of about a million glasses of red wine or something like that. I’d like to try it through at least one bottle of Transmax, though – to see if it really can stop my aging.

I’ve been taking a high dose of resveratrol every day for about a year now, so I was happy to see this article in wired about new strong evidence of its benefits in anti-aging.

“For the first time, we can mimic caloric restriction in an otherwise healthy animal,” said study co-author David Sinclair, a Harvard University biologist and co-founder of Sirtris Pharmaceuticals. “That’s been the goal of the field for decades. We didn’t know it was possible to let an animal eat whatever it wants, but still get the benefits. We now have evidence.”

Regardless of mouse weight and diet, resveratrol worked wonders. At two years of age, or the mouse equivalent of senescence, the mice were more coordinated than their non-dosed counterparts. Their bones were thicker and stronger, their eyes free of cataracts, their hearts beating strong. At the cellular level, tissues displayed gene-level changes almost identical to those produced by caloric restriction.

“The mice had tremendous health benefits from taking resveratrol,” said de Cabo. “If any of those parameters translate to humans, it will be tremendous.”

via tradereyal

California researchers have found that people think more expensive wines taste better, regardless of how they taste.

“We have known for a long time that people’s perceptions are affected by marketing, but now we know that the brain itself is modulated by price,” said Baba Shiv, an associate professor at the Stanford Graduate School of Business, and one of the authors of the study.

I am going to repackage box wine and sell it for $1000 a bottle. Maybe this is why people won’t drink box wine even though it tastes similar to other more expensive wines.
Based on this study you might think that it would be better to sell wine at expensive prices, but Fred Franzia has made a lot of money selling it cheaper than everyone else.

On the chemistryworldblog, there is a post by a reader about resveratrol. It sounds almost identical to my experience:

…after two weeks the results were subtle but undeniable. He said that he had more energy during the day, was more alert throughout the day and was sleeping less but waking up more refreshed.

I still take the 500mg capsules every morning and have been doing so for months. Any other readers taking it? If so, I’m interested in your experience. Leave a comment or send me an email.

SIRT, the company that researches anti-aging and resveratrol, was up 7.8% today and is starting to look pretty nice:

Today there was news about their new resveratrol-like pill.

Their latest research shows these experimental drug compounds — which are 1,000 times more potent than resveratrol — helped reverse diabetes symptoms and reduce insulin sensitivity in two different studies in diabetic mice and one in rats.

The discovery may have implications well beyond diabetes drugs, which is itself a $19 billion global market.

“We will make a drug to treat one disease, but it will, as an added bonus, protect you against most of the other diseases of the Western world.”

Now this is a stock that people could get excited about.